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Cis-Regulatory Accessibility Directs Muller Glial Development and Regenerative Capacity

2019-09-03

Abstract excerpt

Diseases and damage to the retina lead to losses in retinal neurons and eventual visual impairment. Although the mammalian retina has no inherent regenerative capabilities, fish have robust regeneration from Müller glia (MG). Recently, we have shown that driving expression of Ascl1 in adult mouse MG stimulates neurogenesis similar to fish regeneration. The regeneration observed in the mouse is limited in the varie...

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Literature Corpus work
babb204f-52f5-5ee2-8676-ee54140c92cd
DOI
10.1101/752428
Open publication

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Cis-Regulatory Accessibility Directs Muller Glial Development and Regenerative CapacityDOI 10.1101/752428
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