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Cytology and KRAS/GNAS Molecular Testing of Pancreatic Cyst Fluid for Risk Stratification of Intraductal Papillary Mucinous Neoplasms: a Single-Center Study with Histological Correlation

2026-03-25

Abstract excerpt

<h4>Background: </h4> Accurate preoperative risk stratification of intraductal papillary mucinous neoplasms (IPMNs) remains a major challenge in pancreatic surgery. Cytology obtained through endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) demonstrates high specificity but limited sensitivity, whereas molecular analysis of cyst fluid—particularly KRAS and GNAS mutations—has emerged as a promising comp...

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Literature Corpus work: ba9a5759-b1ef-59f0-8546-a15cbc83b128
DOI: 10.20944/preprints202603.2011.v1

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