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Systematic Analysis of the Glucose-PTS in <i>Streptococcus sanguinis</i> Highlighted its Importance in Central Metabolism and Bacterial Fitness

2024-07-25

Abstract excerpt

Previous work reported that deletion of the Enzyme IIAB subunits (EIIAB Man , manL ) of the glucose phosphotransferase system (glucose-PTS, manLMNO) in Streptococcus sanguinis impacted carbon catabolite repression (CCR) and bacterial fitness. Here, a single nucleotide polymorphism in ManN, ManNA91E, produced the unusual phenotype of increased excretion of organic acids and H 2 O 2 , yet elevated PTS activiti...

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Literature Corpus work
51702e08-8ac7-56b9-b0af-a18c9aeacc46
DOI
10.1101/2024.07.25.605150
Open publication

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Systematic Analysis of the Glucose-PTS in <i>Streptococcus sanguinis</i> Highlighted its Importance in Central Metabolism and Bacterial FitnessDOI 10.1101/2024.07.25.605150
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