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Article

Purine Salvage Pathways in the Apicomplexan Parasite Toxoplasma gondii

1 Jul 2004

Abstract excerpt

We have exploited a variety of molecular genetic, biochemical, and genomic techniques to investigate the roles of purine salvage enzymes in the protozoan parasite Toxoplasma gondii. The ability to generate defined genetic knockouts and target transgenes to specific loci demonstrates that T. gondii uses two (and only two) pathways for purine salvage, defined by the enzymes hypoxanthine-xanthine-guanine...

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PMID: 15140885
DOI: 10.1074/jbc.m404232200

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