Article

Sex-specific multi-level 3D genome dynamics in the mouse brain

2021-05-03

Abstract excerpt

The female mammalian brain exhibits sex-hormone-driven plasticity during the reproductive period. Evidence implicates chromatin dynamics in gene regulation underlying this plasticity. However, whether ovarian hormones impact higher-order chromatin organization in post-mitotic neurons in vivo is unknown. Here, we mapped 3D genome of ventral hippocampal neurons across the estrous cycle and by sex in mice. In female...

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Literature Corpus work: 71bc8cf6-7669-52aa-8947-c1f74e649c2e
DOI: 10.1101/2021.05.03.442383

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