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Article

microRNA-184 Induces a Commitment Switch to Epidermal Differentiation

30 Nov 2017

Abstract excerpt

miR-184 is a highly evolutionary conserved microRNA (miRNA) from fly to human. The importance of miR-184 was underscored by the discovery that point mutations in miR-184 gene led to corneal/lens blinding disease. However, miR-184-related function in vivo remained unclear. Here, we report that the miR-184 knockout mouse model displayed increased p63 expression in line with epidermal hyperplasia, while forced...

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PMID: 29198823
DOI: 10.1016/j.stemcr.2017.10.030

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