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Article

MicroRNA-214 controls skin and hair follicle development by modulating the activity of the Wnt pathway.

The Journal of cell biology - 24 Nov 2014

Ahmed Mohammed I, Alam Majid, Emelianov Vladimir U, Poterlowicz Krzysztof, Patel Ankit, Sharov Andrey A, Mardaryev Andrei N, Botchkareva Natalia V

Abstract excerpt

Skin development is governed by complex programs of gene activation and silencing, including microRNA-dependent modulation of gene expression. Here, we show that miR-214 regulates skin morphogenesis and hair follicle (HF) cycling by targeting β-catenin, a key component of the Wnt signaling pathway. miR-214 exhibits differential expression patterns in the skin epithelium, and its inducible overexpression in...

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Identifiers

PMID: 25422376
DOI: 10.1083/jcb.201404001
PMCID: PMC4242830

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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