Article

Cytoprotective effects of hypoxia against oxidative stress in human lens epithelial cells by up-regulating Nrf2 expression

2023-02-14

Abstract excerpt

AIM: To investigate the protective mechanism that hypoxia may attenuate human lens epithelial cells (LECs) injury caused by oxidative stress. METHODS: Human LECs were cultured in different atmospheric levels of O 2 at different 4-Hydroxynonenal (4-HNE) concentrations and detected the viability by CCK-8. The apoptosis, reactive oxygen species (ROS), and senescent level were analyzed in both hypoxia and normoxia cul...

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Literature Corpus work: ba3b0f08-5464-57c4-b721-c26933ac8042
DOI: 10.21203/rs.3.rs-2537515/v1

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