Article

Nanoeugenol Prevents Apoptotic Damage in Selenite-induced Cataracts in Cultured Lenses From Wistar Rats and in Human Lenticular Epithelial Cell Lines: Molecular Validation

2021-03-09

Abstract excerpt

<title>Abstract</title> <p>Senile cataract is the most common cause of severe visual impairment and blindness. Lenticular epithelial cells apoptosis induced by oxidative stress is a major factor in senile cataract pathogenesis, but there are still many blind nodes in this progress. The aim of the present experiment was to investigate the possibility that nanoeugenol prevents selenite-induced cataractogenesis by r...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 34dc2959-3266-5c12-92df-b53608b1603a
DOI: 10.21203/rs.3.rs-260712/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Nanoeugenol Prevents Apoptotic Damage in Selenite-induced Cataracts in Cultured Lenses From Wistar Rats and in Human Lenticular Epithelial Cell Lines: Molecular ValidationDOI 10.21203/rs.3.rs-260712/v1Read

JAG1/Notch Pathway Inhibition Induces Ferroptosis and Promotes CataractogenesisSemantic proximity Read

Comprehensive transcriptomic analysis reveals canonical and novel pathways modulated by nanoceria in mammalian retinal degenerationSemantic proximity Read

Slit2 Promotes H 2 O 2 -Induced Lens Epithelial Cells Oxidative Damage and Age-Related CataractSemantic proximity Read

Mechanisms of the Cytotoxic Effect of Selenium Nanoparticles in Different Human Cancer Cell LinesSemantic proximity Read

Cataract Review of Integrating Pathogenic Mechanisms, Experimental Models, and Therapeutic DevelopmentSemantic proximity Read

Identification of tRNA-derived small RNAs expression profiles and their potential functions in age-related cataractSemantic proximity Read

Cell death pattern in lens epithelium of cataract patientsSemantic proximity Read

MicroRNA-204-5p attenuates oxidative stress, apoptosis and inflammation by targeting TXNIP in diabetic cataractSemantic proximity Read

The role of oxidative stress in the pathogenesis of ocular diseases: an overviewSemantic proximity Read

Involvement of endoplasmic reticulum stress in rotenone-induced leber hereditary optic neuropathy model and the discovery of new therapeutic agents.Semantic proximity Read

MicroRNA-182-5p protects human lens epithelial cells against oxidative stress-induced apoptosis by inhibiting NOX4 and p38 MAPK signallingSemantic proximity Read

Effects of selenium nanoparticles on the ROS levels, oxidative stress, and expression of Bax/Bcl-2 and P53 genes in SW-480 human colon cancer cell lineSemantic proximity Read