Article

Can machine learning aid in identifying disease genes? The case of autism spectrum disorder

2020-11-27

Abstract excerpt

Discovering genes involved in complex human genetic disorders is a major challenge. Many have suggested that machine learning (ML) algorithms using gene networks can be used to supplement traditional genetic association-based approaches to predict or prioritize disease genes. However, questions have been raised about the utility of ML methods for this type of task due to biases within the data, and poor real-world...

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Literature Corpus work: ba291079-fcfd-5047-92a8-f6d53a31d8d8
DOI: 10.1101/2020.11.26.394676

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