Article
Brain-specific functional relationship networks inform autism spectrum disorder gene prediction.
Translational psychiatry - 6 Mar 2018
Duda Marlena, Zhang Hongjiu, Li Hong-Dong, Wall Dennis P, Burmeister Margit, Guan Yuanfang
Abstract excerpt
Autism spectrum disorder (ASD) is a neuropsychiatric disorder with strong evidence of genetic contribution, and increased research efforts have resulted in an ever-growing list of ASD candidate genes. However, only a fraction of the hundreds of nominated ASD-related genes have identified de novo or transmitted loss of function (LOF) mutations that can be directly attributed to the disorder. For this reason, a...
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