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Article

Network- and attribute-based classifiers can prioritize genes and pathways for autism spectrum disorders and intellectual disability.

American journal of medical genetics. Part C, Seminars in medical genetics - 15 May 2012

Kou Yan, Betancur Catalina, Xu Huilei, Buxbaum Joseph D, Ma'ayan Avi

Abstract excerpt

Autism spectrum disorders (ASD) are a group of related neurodevelopmental disorders with significant combined prevalence (∼1%) and high heritability. Dozens of individually rare genes and loci associated with high-risk for ASD have been identified, which overlap extensively with genes for intellectual disability (ID). However, studies indicate that there may be hundreds of genes that remain to be identified. The...

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Identifiers

PMID: 22499558
DOI: 10.1002/ajmg.c.31330
PMCID: PMC3505691

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