Article

A machine learning approach to predicting autism risk genes: Validation of known genes and discovery of new candidates

2018-11-07

Abstract excerpt

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition with a strong genetic basis. The role of de novo mutations in ASD has been well established, but the set of genes implicated to date is still far from complete. The current study employs a machine learning-based approach to predict ASD risk genes using features from spatiotemporal gene expression patterns in human brain, gene-level constrain...

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Literature Corpus work: 43dd8614-0b05-5319-8618-d4cfa9db79d2
DOI: 10.1101/463547

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