Article
Diversity of Influenza A(H5N1) Viruses in Infected Humans, Northern Vietnam, 2004-2010.
Emerging infectious diseases - 1 Jul 2018
Imai Hirotaka, Dinis Jorge M, Zhong Gongxun, Moncla Louise H, Lopes Tiago J S, McBride Ryan, Thompson Andrew J, Peng Wenjie, Le Mai Thi Q, Hanson Anthony, Lauck Michael, Sakai-Tagawa Yuko, Yamada Shinya, Eggenberger Julie, O'Connor David H, Suzuki Yasuo, Hatta Masato, Paulson James C, Neumann Gabriele, Friedrich Thomas C, Kawaoka Yoshihiro
Abstract excerpt
Influenza viruses exist in each host as a collection of genetically diverse variants, which might enhance their adaptive potential. To assess the genetic and functional diversity of highly pathogenic avian influenza A(H5N1) viruses within infected humans, we used deep-sequencing methods to characterize samples obtained from infected patients in northern Vietnam during 2004-2010 on different days after infection,...
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