Article

Machine Learning-Based Identification of Sickle Cell Disease Subphenotypes in Clinical Trial Data

2025-06-02

Abstract excerpt

Sickle Cell Disease (SCD) is a rare autosomal recessive disorder caused by a point mutation producing abnormal hemoglobin S, leading to deformed red blood cells and a wide range of clinical manifestations, including pain crises, organ damage, and an increased risk of infection. These devastating complications often result in significant morbidity and early mortality, presenting significant therapeutic challenges....

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Literature Corpus work: b9c91dfa-a024-5c24-b9fb-d4e05e7dc178
DOI: 10.1101/2025.06.01.25328537

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