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Article

Phenotypes of sickle cell intensive care admissions: an unsupervised machine learning approach in a single-center retrospective cohort.

Annals of hematology - 1 Sept 2022

Padrão Eduardo Messias Hirano, Bustos Brian, Mahesh Ashwin, Fonseca Guilherme Henrique Hencklain, Taniguchi Leandro Utino

Abstract excerpt

Sickle cell disease (SCD) is associated with multiple known complications and increased mortality. This study aims to further understand the profile of intensive care unit (ICU) admissions of SCD patients. In this single-center retrospective cohort (approval number 0926-11), we evaluated SCD-related ICU admissions at our hospital in São Paulo, Brazil. Admissions were clustered using clinical data and organ...

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PMID: 35836008
DOI: 10.1007/s00277-022-04918-4

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