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Article

Accurate identification of sickle cell disease cases in a large genotyped cohort using electronic health record data.

Blood advances - 9 Jun 2026

Wuichet Kristin, Corty Robert, Bick Alexander, DeBaun Michael R

Abstract excerpt

ABSTRACT: The US Food and Drug Administration recently approved sickle cell disease (SCD) gene therapies that require a contemporaneous cohort to compare their outcomes with those of individuals who did not receive gene therapy. Previously, we developed an automated algorithm to create a contemporaneous cohort of children and adults with SCD using electronic health record data. We tested the hypothesis that the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41921205
DOI: 10.1182/bloodadvances.2025018414
PMCID: PMC13251667

Genes

SCD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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