Article

From Genomics to Therapy: Repurposing Approved Drugs and Identifying Novel Targets for Sickle Cell Disease in Saudi Patients

2025-06-26

Abstract excerpt

<h4>Background: </h4> Sickle cell disease (SCD) is an inherited blood disorder characterized by chronic hemolysis, inflammation, and vaso-occlusive crises (VOC), leading to several complications and reduced life expectancy of affected individuals. Limited effective treatment options are currently available; however, pharmacogenomic (PGx) insights derived from recent genomic findings, particularly in underrepresent...

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Literature Corpus work: c9ea781f-e475-5dde-88c4-7738bc02b5ef
DOI: 10.20944/preprints202506.2151.v1

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