Article

Necroptotic Signaling Orchestrates GBM Malignancy and Potentiates Temozolomide Response

2025-09-17

Abstract excerpt

<title>Abstract</title> <p>Glioblastoma (GBM), a highly aggressive form of glioma, poses serious harm to patients due to its extremely poor prognosis and severe resistance to chemotherapeutic agents. Although programmed necrosis (necroptosis) has been implicated in GBM progression, its precise function and biological significance in GBM remain incompletely defined. Here, we show that elevated expression of key ne...

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Literature Corpus work: b9c0d3d9-80aa-5da3-be03-193cf5abd4f1
DOI: 10.21203/rs.3.rs-7286420/v1

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