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Article

RIPK3 is a novel prognostic marker for lower grade glioma and further enriches IDH mutational status subgrouping.

Journal of neuro-oncology - 1 May 2020

Vergara Guilherme Afonso, Eugenio Gisele Cristine, Malheiros Suzana Maria Fleury, Victor Elivane da Silva, Weinlich Ricardo

Abstract excerpt

PURPOSE: Necroptosis is a necrotic-like cell death pathway in which Receptor-interacting serine/threonine-protein kinase 3 (RIPK3) plays a central role and may induce inflammation and immunity. Lower RIPK3 levels have been correlated with a poor prognosis in breast and colorectal cancer patients. Instead, in gliomas, the most prevalent among central nervous system cancers, necrosis concurs with a more aggressive...

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Identifiers

PMID: 32222932
DOI: 10.1007/s11060-020-03473-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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