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<i>In vivo</i> human embryonic spinal cord atlas validates stem cell–derived human dorsal interneurons and reveals ASD spinal signatures

2025-12-24

Abstract excerpt

Restoring somatosensory function after spinal cord injury (SCI) faces fundamental challenges: neuronal subtypes must match both axial position and circuit identity, yet the developmental patterning of human dorsal spinal interneurons (dIs) remains incompletely defined. Here, we integrate six single-cell transcriptomics datasets derived from human embryonic spinal cord tissue spanning gestational weeks 4-25 to gene...

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Literature Corpus work
b970ce7e-1658-509a-bda0-fe095deee6cc
DOI
10.64898/2025.12.22.696129
Open publication

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<i>In vivo</i> human embryonic spinal cord atlas validates stem cell–derived human dorsal interneurons and reveals ASD spinal signaturesDOI 10.64898/2025.12.22.696129
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