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Hierarchical lineage architecture of human and avian spinal cord revealed by single-cell genomic barcoding

2025-10-24

Abstract excerpt

The formation of neural circuits depends on the precise spatial and temporal organisation of neuronal populations during development. In the vertebrate spinal cord, progenitors are patterned into molecularly defined domains, but how lineage relationships shape neuronal diversity and function has remained unclear. Here, we combine genomic barcoding with single- cell RNA sequencing in chick and human embryos to gene...

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Literature Corpus work
27b192c6-d091-5385-88ba-1f8e0cb9a51d
DOI
10.1101/2025.10.24.684328
Open publication

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Hierarchical lineage architecture of human and avian spinal cord revealed by single-cell genomic barcodingDOI 10.1101/2025.10.24.684328
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