Article

Single-Soma Deep RNA Sequencing of Human Dorsal Root Ganglion Neurons Reveals Novel Molecular and Cellular Mechanisms Underlying Somatosensation

2023-09-15

Abstract excerpt

<title>Abstract</title> <p>The versatility of somatosensation arises from heterogeneous dorsal root ganglion (DRG) neurons. However, soma transcriptomes of individual human DRG (hDRG) neurons – critical information to decipher their functions – are lacking due to technical difficulties. Here, we developed a novel approach to isolate individual hDRG neuron somas for deep RNA sequencing (RNA-seq). On average, >9,00...

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Literature Corpus work: f1be3298-a226-5724-af1a-f23d4f2dc3ac
DOI: 10.21203/rs.3.rs-3293629/v1

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