Article

Fast, accurate antibody structure prediction from deep learning on massive set of natural antibodies

2022-04-21

Abstract excerpt

Antibodies have the capacity to bind a diverse set of antigens, and they have become critical therapeutics and diagnostic molecules. The binding of antibodies is facilitated by a set of six hypervariable loops that are diversified through genetic recombination and mutation. Even with recent advances, accurate structural prediction of these loops remains a challenge. Here, we present IgFold, a fast deep learning me...

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Literature Corpus work: 8cdd7698-d265-52a5-9aeb-52ab445fe369
DOI: 10.1101/2022.04.20.488972

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