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The FUR-like regulators PerRA and PerRB integrate a complex regulatory network that promotes mammalian host-adaptation and virulence of <i>Leptospira interrogans</i>

2020-11-05

Abstract excerpt

Leptospira interrogans , the causative agent of most cases of human leptospirosis, must respond to myriad environmental signals during its free-living and pathogenic lifestyles. Previously, we compared L. interrogans cultivated in vitro and in vivo using a dialysis membrane chamber (DMC) peritoneal implant model. From these studies emerged the importance of genes encoding the Peroxide responsive regulators PerR...

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Literature Corpus work
b9418190-eef1-5d5c-83e8-60e496884cc0
DOI
10.1101/2020.11.05.369660
Open publication

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