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The adaptive transcriptional response of pathogenic <i>Leptospira</i> to peroxide reveals new defenses against infection-related oxidative stress

2020-04-04

Abstract excerpt

Pathogenic Leptospira spp. are the causative agents of the waterborne zoonotic disease leptospirosis. During infection, Leptospira are confronted with dramatic adverse environmental changes such as deadly reactive oxygen species (ROS). Withstanding ROS produced by the host innate immunity is an important strategy evolved by pathogenic Leptospira for persisting in and colonizing hosts. In L. interrogans , genes...

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Literature Corpus work
ebbf8cd7-41c2-5c2b-b689-12d48a42d621
DOI
10.1101/2020.04.03.015982
Open publication

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The adaptive transcriptional response of pathogenic <i>Leptospira</i> to peroxide reveals new defenses against infection-related oxidative stressDOI 10.1101/2020.04.03.015982
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