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Article

Heme rescues a two-component system Leptospira biflexa mutant.

BMC microbiology - 30 Jan 2008

Louvel Hélène, Betton Jean-Michel, Picardeau Mathieu

Abstract excerpt

BACKGROUND: Heme is typically a major iron source for bacteria, but little is known about how bacteria of the Leptospira genus, composed of both saprophytic and pathogenic species, access heme. RESULTS: In this study, we analysed a two-component system of the saprophyte Leptospira biflexa. In vitro phosphorylation and site-directed mutagenesis assays showed that Hklep is a histidine kinase which, after...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18234085
DOI: 10.1186/1471-2180-8-25
PMCID: PMC2266917

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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