Article

Novel insights into the common heritable liability to addiction: a multivariate genome-wide association study

2021-11-19

Abstract excerpt

Addiction to nicotine, alcohol and cannabis commonly co-occurs, which is thought to partly stem from a common heritable liability. To elucidate its genetic architecture, we modelled the common liability to addiction, inferred from genetic correlations among six measures of dependence and frequency of use of nicotine, alcohol and cannabis. Forty-two genetic variants were identified in the multivariate genome-wide a...

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Literature Corpus work: b9211e79-0cf1-51cc-9895-766a7adaf5e4
DOI: 10.1101/2021.11.19.21266548

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