Article

Transcriptomic and Proteomic Spatial Profiling of Pediatric and Adult Diffuse Midline Glioma H3 K27-Altered, Reveals Region Specific Differences and Limited Overlap between mRNA and Protein

2024-04-05

Abstract excerpt

<title>Abstract</title> <p>Diffuse midline glioma, <italic>H3 K27</italic>-altered (DMG-Alt) are highly aggressive malignancies of the central nervous system (CNS) that primarily affect the pediatric population. Large scale spatial transcriptomic studies have implicated that tumor microenvironmental landscape plays an important role in determining the phenotypic differences in tumor presentation and clinical cour...

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Literature Corpus work: b8ef9f9e-a558-5aea-9b3a-1e7cc92fa21a
DOI: 10.21203/rs.3.rs-4139314/v1

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