Article

Evolutionary dynamics of pseudoautosomal region 1 in humans and great apes

2021-09-15

Abstract excerpt

The pseudoautosomal region 1 (PAR1) is a 2.7 Mb telomeric region of human sex chromosomes. As the largest point of contact between the X and Y, PAR1 has a crucial role in ensuring proper segregation of sex chromosomes during male meiosis, exposing it to extreme recombination and associated mutational processes. We investigate PAR1 evolution using population genomic datasets of extant humans, eight populations of g...

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Literature Corpus work: b837a3cd-78fd-5513-8f85-ae20d5e04a6f
DOI: 10.1101/2021.09.14.460222

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