Article

Interplay between Sex and Disease Burden in Huntington’s Disease: Clinical and Neuroimaging Perspectives

2024-11-02

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Huntington’s disease (HD) is a progressive neurodegenerative disorder caused by a cytosine-adenine-guanine (CAG) repeat expansion in the hungtintin gene. The disease exhibits sex-related differences in symptomatology and disease progression, but the effect on brain structural biomarkers and the interaction between sex and disease burden remain underexplored. <h4>Objectives</h4...

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Literature Corpus work: b869b58e-1bbf-594c-bee7-a8105dd0645a
DOI: 10.1101/2024.10.31.24315900

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