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Huntington’s Disease Integrated Staging System (HD-ISS): A Novel Evidence-Based Classification System For Staging

2021-09-11

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Despite the monogenic autosomal dominant nature of Huntington’s disease (HD), the current research paradigm is still based on overt clinical phenotypes and does not address disease pathobiology and biomarkers that are evident decades before functional decline. A new research framework is needed to standardize clinical research and enable interventional studies earlier in the c...

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Literature Corpus work
5b6edce0-6c77-547c-97b1-24eb3d62b446
DOI
10.1101/2021.09.01.21262503
Open publication

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