Article

Megakaryocytes, erythropoietic and granulopoietic cells express CAL2 antibody in myeloproliferative neoplasms carrying CALR gene mutations

2019-12-30

Abstract excerpt

<h4>Summary</h4> The discovery of mutated Calreticulin (CALR) in myeloproliferative neoplasms (MPN) has provided proof of clonality, diagnostic importance, and influence on prognosis of this pathology. The identification of this MPN-associated driver mutation -currently based on molecular assays- is represented as a major diagnostic criterion for essential thrombocythaemia (ET), pre-fibrotic myelofibrosis and pri...

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Literature Corpus work: b859675b-c8bc-5966-a4e5-933c7f2692dd
DOI: 10.1101/2019.12.22.886317

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