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Article

Megakaryocytes, erythropoietic and granulopoietic cells express CAL2 antibody in myeloproliferative neoplasms carrying CALR gene mutations.

International journal of experimental pathology - 1 Feb 2021

Ali Hebah, Puccio Ignazio, Akarca Ayse U, Bob Roshanak, Pomplun Sabine, Keong Wong Wai, Gupta Rajeev, Sekhar Mallika, Lambert Jonathan, Al-Masri Hytham, Stein Harald, Marafioti Teresa

Abstract excerpt

Testing for the CALR mutation is included in the updated WHO criteria for essential thrombocythaemia (ET) and primary myelofibrosis (PMF). We report on the application of the CAL2 monoclonal antibody, raised against the mutated CALR gene to myeloid cases. The immunostain was used on 116 acute myeloid leukaemias (AML) and 66 myeloproliferative neoplasms (MPN) or myelodysplastic syndromes/myeloproliferative...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32929772
DOI: 10.1111/iep.12375
PMCID: PMC7839955

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Megakaryocytes, erythropoietic and granulopoietic cells express CAL2 antibody in myeloproliferative neoplasms carrying CALR gene mutations.PMID 32929772Read ↗

Megakaryocytes, erythropoietic and granulopoietic cells express CAL2 antibody in myeloproliferative neoplasms carrying CALR gene mutationsSemantic proximity Read ↗

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