Article

BRG1 is a prognostic indicator and a potential therapeutic target for prostate cancer

2018-12-27

Abstract excerpt

BRG1 is one of two mutually exclusive ATPases that function as the catalytic subunit of human SWI/SNF chromatin remodeling enzymes. BRG1 has been identified as a tumor suppressor in some cancer types but has been shown to be expressed at elevated levels, relative to normal tissue, in other cancers. Using the TCGA (The Cancer Genome Atlas) prostate cancer database, we determined that BRG1 mRNA and protein expressio...

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Literature Corpus work: b850958c-19bf-595b-96b8-b29d22236ada
DOI: 10.1101/506972

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