Article
The ADRB1 (Adrenoceptor Beta 1) and ADRB2 genes significantly co-express with commonly mutated genes in prostate cancer.
Discovery medicine - 1 Jan 2000
Lehrer Steven, Rheinstein Peter H
Abstract excerpt
BACKGROUND: Beta blockers act on the beta-adrenergic receptors ADRB1 and ADRB2 to reduce heart rate and blood pressure. Observational studies have revealed strong risk reductions in metastasis and cancer-specific mortality with the use of beta-blockers in patients with some cancers. But observational studies of prostate cancer have reported conflicting results. OBJECTIVES: We examined the relationship of ADRB1...
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