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A novel RofA-family transcriptional regulator, GadR, controls the development of acid resistance in <i>Listeria monocytogenes</i>

2023-06-22

Abstract excerpt

Stomach acid provides a significant innate barrier to the entry of the food-borne pathogen Listeria monocytogenes into the human gastrointestinal tract. A key determinant of acid resistance in this bacterium is the conserved glutamate decarboxylase system, GadD2 (encoded by the gadT2D2 operon), which helps to maintain the intracellular pH during exposure to gastric acid. In this study, we identified a premature...

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Literature Corpus work
b8424fa3-6a29-56a6-9505-68b43963d4aa
DOI
10.1101/2023.06.22.546042
Open publication

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