Article
Identification of sigma factor sigma B-controlled genes and their impact on acid stress, high hydrostatic pressure, and freeze survival in Listeria monocytogenes EGD-e.
Applied and environmental microbiology - 1 Jun 2004
Wemekamp-Kamphuis Henrike H, Wouters Jeroen A, de Leeuw Patrick P L A, Hain Torsten, Chakraborty Trinad, Abee Tjakko
Abstract excerpt
The gene encoding the alternative sigma factor sigma(B) in Listeria monocytogenes is induced upon exposure of cells to several stresses. In this study, we investigated the impact of a sigB null mutation on the survival of L. monocytogenes EGD-e at low pH, during high-hydrostatic-pressure treatment, and during freezing. The survival of Delta sigB mutant exponential-phase cells at pH 2.5 was 10,000-fold lower than...
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