The hdeD Gene Represses the Expression of Flagellum Biosynthesis via LrhA in Escherichia coli K-12.

doi:10.1128/JB.00420-21

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Article

The hdeD Gene Represses the Expression of Flagellum Biosynthesis via LrhA in Escherichia coli K-12.

Journal of bacteriology - 18 Jan 2022

Yamanaka Yuki, Aizawa Shin-Ichi, Yamamoto Kaneyoshi

Abstract excerpt

Escherichia coli survives under acid stress conditions by the glutamic acid-dependent acid resistance (GAD) system, which enzymatically decreases intracellular protons. We found a linkage between GAD and flagellar systems in E. coli. The hdeD gene, one of the GAD cluster genes, encodes an uncharacterized membrane protein. A reporter assay showed that the hdeD promoter was induced in a GadE-dependent manner when...

Topics

Escherichia coli K12
Escherichia coli Proteins
Flagella
Gene Expression Regulation, Bacterial
Genome, Bacterial
Membrane Proteins
Mutation
Transcription Factors
Transcriptome

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Identifiers

PMID: 34694904
DOI: 10.1128/JB.00420-21
PMCID: PMC8765402

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