Investigation of Osteoprotegerin Gene polymorphisms and Serum level as a predictive marker of cardiac abnormalities in beta thalassemia major

Abstract excerpt

<title>Abstract</title> <p> Background Osteoprotegrin is a protein which Prevents excessive bone resorption by binding to the relevant receptor and its genetic variations may contribute to the development of heart disorders. Materials and Methods Eighty-two beta-thalassemia major patients of Sorour medical center of Mashhad, Iran who were older than 11 years old enrolled for the study. Two dimensional and M-mode...

Topics

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• beta-Thalassemia
• Diastole
• Heart Defects, Congenital
• Hypertrophy, Left Ventricular
• Logistic Models
• Osteoprotegerin
• RANK Ligand
• Receptor Activator of Nuclear Factor-kappa B

Identifiers and source

Literature Corpus work

b7b85b00-1017-55e2-b7e3-06feaaaf8d3a

DOI

10.21203/rs.3.rs-7024553/v1