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Article

Investigation of OPG/RANK/RANKL Genes as a Genetic Marker for Cardiac abnormalities in Thalassemia Major Patients.

Annals of human genetics - 1 May 2017

Singh Mable Misha, Kumar Ravindra, Tewari Satyendra, Agarwal Sarita

Abstract excerpt

OBJECTIVE: The aim of the study was to investigate the role of osteoprotegerin (OPG)/RANK/RANKL variants in left ventricular hypertrophy (LVH) and diastolic dysfunction in thalassemia major patients MATERIALS AND METHOD: One hundred and five beta-thalassemia patients who were older than 10 years of age were enrolled for the study. Two-dimensional and M-mode echocardiography analysis was done in all patients....

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Share to beta-Thalassemia
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Share to Heart Defects, Congenital

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypertrophy, Left Ventricular

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Share to Osteoprotegerin

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Share to Receptor Activator of Nuclear Factor-kappa B

Source

Identifiers

PMID: 28244588
DOI: 10.1111/ahg.12189

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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