Article
Apolipoprotein E gene polymorphism and the risk of left ventricular dysfunction among Egyptian β-thalassemia major.
Gene - 25 Jul 2013
El-Tagui Mona H, Hamdy Mona M, Shaheen Iman A, Agha Hala, Abd-Elfatah Hoda A
Abstract excerpt
In Egypt, β-thalassemia is the most common hereditary hemolytic anemia. Cardiac dysfunction, secondary to iron overload with formation of oxygen free radicals, is the most common cause of death in β-thalassemia patients. This study was designed to determine whether the allelic genotype of apolipoprotein E (Apo E), which exhibits antioxidant properties, could represent a genetic risk factor for the development of...
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