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Article

OPG/RANK/RANKL axis relation to cardiac iron-overload in children with transfusion-dependent thalassemia.

Scientific reports - 2 Aug 2023

Sayed Samira Zein, Abd El-Hafez Asmaa Hosni, Abu El-Ela Mostafa Ahmed, Mourad Mohamed Aboul-Fotouh, Mousa Suzan Omar

Abstract excerpt

OPG/RANK/RANKL axis was reportedly involved in initiating various diseases, especially bone and cardiovascular diseases. This study aimed to assess the relationship between some OPG, RANK, and RANKL polymorphisms and alleles and iron-overload-induced cardiomyopathy in children with transfusion-dependent thalassemia (TDT). This study included 80 TDT children and 80 age and sex-matched controls. Real-time PCR was...

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Identifiers

PMID: 37532711
DOI: 10.1038/s41598-023-39596-3
PMCID: PMC10397306

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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