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Article

VRK1 kinase maintains an undifferentiated proliferative state in neuroblastoma tumor cells

2026-08-05

Abstract excerpt

Neuroblastoma is a neural crest-derived pediatric malignancy characterized by marked cellular heterogeneity and variable differentiation status. Undifferentiated tumors are associated with aggressive clinical behavior, treatment resistance and poor outcome, highlighting the need to identify molecular mechanisms that sustain tumor cell plasticity and prevent differentiation. Vaccinia-related kinase 1 (VRK1) is a se...

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Literature Corpus work
b775a27c-e250-5aac-9c6c-7b446ba20c46
DOI
10.64898/2026.08.05.742965
Open publication

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VRK1 kinase maintains an undifferentiated proliferative state in neuroblastoma tumor cellsDOI 10.64898/2026.08.05.742965
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