Article
Neuroblastoma: A Tough Nut to Crack.
American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting - 1 Jan 2016
Speleman Frank, Park Julie R, Henderson Tara O
Abstract excerpt
Neuroblastoma, an embryonal tumor arising from neural crest-derived progenitor cells, is the most common solid tumor in childhood, with more than 700 cases diagnosed per year in the United States. In the past several decades, significant advances have been made in the treatment of neuroblastoma. Treatment advances reflect improved understanding of the biology of neuroblastoma. Although amplification of MYCN was...
Topics
- Anaplastic Lymphoma Kinase
- DNA Copy Number Variations
- Gene Regulatory Networks
- Humans
- Molecular Targeted Therapy
- Mutation
- N-Myc Proto-Oncogene Protein
- Neuroblastoma
- Prognosis
- RNA-Binding Proteins
- Receptor Protein-Tyrosine Kinases
- Signal Transduction