Article

Tissue-specific cells generated to predict xenogeneic immune responses demonstrate that SLA-downregulated kidney proximal tubular epithelial cells are low immunogenic

2023-02-10

Abstract excerpt

Patients with kidney failure depend on transplantation as the only curative option. Xenotransplantation re-emerged as a promising alternative to enlarge the available organ pool. However, the success of xenotransplantation depends on the design and selection of specific genetic modifications and on the development of robust assays allowing for a precise assessment of tissue-specific immune responses. Nevertheless,...

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Literature Corpus work: b7523f6d-8fee-5da5-af01-dae266d78388
DOI: 10.21203/rs.3.rs-2519870/v1

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Tissue-specific cells generated to predict xenogeneic immune responses demonstrate that SLA-downregulated kidney proximal tubular epithelial cells are low immunogenicDOI 10.21203/rs.3.rs-2519870/v1Read

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