Article

Diversification of the recombinant anti-kinesin monoclonal antibody H2

2022-12-22

Abstract excerpt

Kinesin-1, a motor protein composed of the kinesin heavy chain (KHC) and the kinesin light chain (KLC), is fundamental to cellular morphogenesis and function. A monoclonal antibody (mAb) called H2 recognizes the KHC in a broad range of species and is one of the most widely used mAbs in cytoskeletal motor research. Here, we generated vectors that expressed recombinant H2 in mammalian cells. We demonstrated that the...

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Literature Corpus work: b750e343-957d-557e-befe-a341082657ea
DOI: 10.1101/2022.12.22.521561

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