Article

Early alterations of RNA binding protein (RBP) homeostasis and ER stress-mediated autophagy triggers progressive retinal degeneration in the rd10 mouse model of retinitis pigmentosa (RP)

2022-08-19

Abstract excerpt

<title>Abstract</title> The retinal degeneration 10 (<italic>rd10</italic>) mouse model is widely used to study retinitis pigmentosa (RP) pathomechanisms. It offers a rather unique opportunity to study trans-neuronal degeneration because the cell populations in question are separated anatomically and the mutated Pde6b gene is selectively expressed in rod photoreceptors. We hypothesized that RNA binding protein...

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Literature Corpus work: b74225f0-6c91-58f9-8a17-76e508ef46d5
DOI: 10.21203/rs.3.rs-1937402/v1

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