Article
Jointly characterizing epigenetic dynamics across multiple human cell types.
Nucleic acids research - 19 Aug 2016
Zhang Yu, An Lin, Yue Feng, Hardison Ross C
Abstract excerpt
Advanced sequencing technologies have generated a plethora of data for many chromatin marks in multiple tissues and cell types, yet there is lack of a generalized tool for optimal utility of those data. A major challenge is to quantitatively model the epigenetic dynamics across both the genome and many cell types for understanding their impacts on differential gene regulation and disease. We introduce IDEAS, an...
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