Article

Fatty acid desaturation and lipoxygenase pathways support trained immunity

2023-08-22

Abstract excerpt

Infections and vaccinations can induce long-term enhanced responses of innate immune cells to heterologous stimuli, establishing a de facto innate immunological memory termed trained immunity . Monocytes exposed to the Bacillus Calmette-Guérin (BCG) vaccine, have a trained immunity phenotype, characterized by an increased biosynthesis of different lipid mediators (LMs) derived from long-chain polyunsaturated fat...

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Literature Corpus work: b72934fc-87f4-5f8e-a985-96f07945af0f
DOI: 10.1101/2023.08.22.554295

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